Washington Chromatography Discussion Group (WCDG) meets monthly from September to May. Meetings are currently being held virtually.
November 18, 2020
Joint meeting with Chemical Society of Washington (CSW)
A Survey of Cannabinoids in Hemp-Derived Products from the United States Marketplace
Geoffrey A. Dubrow, FDA Center for Food Safety and Applied Nutrition
Abstract: The 2018 Agricultural Improvement Act removed hemp from Schedule I control, creating a market for hemp products, including cannabidiol-containing products. Due to the market’s rapid growth, little is known about the presence and concentration of cannabinoids in commercial products. In the present study, 11 cannabinoids were quantified using liquid chromatography with diode-array detection in a non-representative sampling of 147 products labeled as containing hemp or cannabidiol. Cannabinoid content ranged from 0–143 mg/serving, with a median of 16.7 mg/serving. Fewer than half of products surveyed contained cannabidiol concentrations within 20% of their label declarations. Most products presented concentrations of ∆9-tetrahydrocannabinol below LOQ. These findings emphasize the need for further testing and representative investigation of the cannabidiol marketplace.
Bio: Dr. Geoffrey A. Dubrow is a staff fellow in the Office of Regulatory Science within FDA’s Center for Food Safety and Applied Nutrition. At CFSAN, his work focuses on the analysis of cannabinoids in hemp-containing products. Prior to his work at FDA, Geoff completed his PhD in food science and technology at the Ohio State University in 2019, focusing on the use of untargeted LC/MS and GC/MS “flavoromics” to understand chemical drivers of consumer acceptability in strawberry jams. Beyond food safety, his research interests include the application of chemometrics and metabolomics towards the understanding of food and flavor chemistry, and high-throughput sample preparation.
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